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OCR: Genetic factors that may contribute to th netic pathogenesis of Graves' disease. Some & s' disease factors which may be important in Grav appears are listed in Fig. 17.15. While the TSH-R T-cell unaltered, there are reported changes in antibodies receptors of intrathyroidal T cells. TSH-F mber of relatively appear to be derived from a restricted nu B-cell clones, HLA/DR3 associations are weak and disappointing. The female sex at of all of predominance of Graves' disease, and th ra role for the autoimmune thyroid diseases, favor emale sex hormones